Isolation and Characterization of Saccharomyces cerevisiae with Antagonistic Activity against Salmonella pullorum

Date Received: Nov 01, 2025

Date Accepted: Dec 30, 2025

Date Published: Dec 31, 2025

DOI: https://doi.org/10.31817/vjas.2025.8.4.08

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Issue: Vol. 8 No. 4 (2025): Vietnam Journal of Agricultural Sciences

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ANIMAL SCIENCE – VETERINARY MEDICINE – AQUACULTURE

How to Cite:

Lan, N., Hiep, T., Son, H., Thang, N., Hang, N., Huyen, N., … Duc, H. (2025). Isolation and Characterization of Saccharomyces cerevisiae with Antagonistic Activity against Salmonella pullorum. Vietnam Journal of Agricultural Sciences, 8(4), 2756–2763. https://doi.org/10.31817/vjas.2025.8.4.08

Isolation and Characterization of Saccharomyces cerevisiae with Antagonistic Activity against Salmonella pullorum

Nguyen Thi Lan 1 , Tran Hiep 2 , Hoang Minh Son 1 , Nguyen Van Thang 1 , Nguyen Thi Thu Hang 1 , Nguyen Thi Huyen 1 , Truong Long Van 3   , Hoang Minh Duc (*) 1

  • Corresponding author: [email protected]
  • 1 Faculty of Veterinary Medicine, Vietnam National University of Agriculture, Hanoi 12400, Vietnam
  • 2 Faculty of Animal Science, Vietnam National University of Agriculture, Hanoi 12400, Vietnam
  • 3 Tan Viet Biology Technology Joint Stock Company, Ninh Binh 8100, Vietnam

    • Keywords

    Probiotics, Saccharomyces cerevisiae, Salmonella pullorum, poultry, antibiotic resistance

    Abstract


    Saccharomyces cerevisiae is considered to be an alternative to antibiotics in reducing the growth of pathogenic bacteria and enhancing the mucosal immune system. In countries with developed livestock industries, antibiotic resistance of Salmonella pullorum is still causing difficulties in controlling Pullorum disease. This study aimed to isolate and select S. cerevisiae strains with antagonistic activity against S. pullorum for potential application in probiotics production. A total of eight S. cerevisiae strains were isolated from 50 ripe mango samples. All the isolated strains exhibited inhibitory effects against S. pullorum. Among them, strains SC1, SC6, and SC8 showed strong antagonism, with inhibition zone diameters of 16 ± 0.87mm, 16 ± 0.50mm, and 17 ± 1.80mm, respectively. These isolates exhibited high stability under various conditions. These findings suggest that S. cerevisiae strains SC1, SC6, and SC8 are potential candidates for producing a probiotic to control poultry diseases.

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