In the context of precision machining, predicting the Remaining Useful Life (RUL) of cutting tools plays a critical role in optimizing production processes and reducing maintenance costs. This study proposes and develops four machine learning models for predicting tool RUL in milling operations, including Exponential Gaussian Process Regression (GPR), Fine Tree, Linear Regression, and Quadratic Support Vector Machine (SVM). The input dataset is constructed from sensor signals and key process parameters, including three-axis vibrations (vibration_x, vibration_y, vibration_z), acoustic emission signals, spindle load, cutting speed, feed rate, material hardness, and tool wear. The models are trained and evaluated using standard performance metrics, namely the coefficient of determination (R²), root mean square error (RMSE), and mean absolute error (MAE). Experimental results indicate that the Linear Regression model outperforms the other models, achieving an R² value of 1 and extremely low prediction errors (RMSE = 4.1 × 10⁻⁸; MAE = 3.2 × 10⁻⁸). The findings suggest that the proposed framework is both effective and highly applicable for tool condition monitoring, while also supporting the optimization of cutting parameters in milling processes.