This study explores the phytochemical composition and biological effects of Ficus racemosa bark extracts using various solvents (acetone, hexane, methanol, ethanol, aqueous mixtures). The presence of bioactive compounds, including glycosides, steroids, tannins, polyphenols, and flavonoids was analyzed. Antioxidant potential was assessed via DPPH free radical scavenging and ferric reducing power assays. In the DPPH assay, IC50 values ranged from 5.55 to 9.89 mgL-1, with the ethanol extract (S4) showing the lowest IC50 (5.55 mg.L-1), surpassing vitamin C (IC50 = 6.18 mg.L-1). The ferric reducing power assay indicated that the methanol extract (S2) exhibited the highest antioxidant capacity with an EC50 of 7.59 mg.L-1, 3.5 times lower than that of the BHA standard (26.82 mg.L-1). In vitro α-glucosidase inhibition assays revealed that all extracts effectively suppressed enzyme activity , with IC50 values from 0.049 mg.L-1 (S4) to 0.66 mg.L-1 (S1), significantly lower than acarbose (IC50 = 156.16 mg.L-1). Additionally, the extracts markedly reduced nitric oxide production in LPS-stimulated RAW 264.7 macrophages, with IC50 values between 62.08 and 182.47 µg.mL-1, compared to the positive control L-NMMA (IC50 = 11.91 µg.mL-1). These findings highlight the potent antioxidant, anti-diabetic, and anti-inflammatory properties of F. racemosa bark extracts, supporting their potential as natural therapeutic agents.